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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Nat Genet. 2008 Dec 7;41(1):77–81. doi: 10.1038/ng.290

Figure 1. Regional plot of fasting glucose association results for the MTNR1B locus across 10 MAGIC GWAS.

Figure 1

Meta-analysis -log10 P-values are plotted as a function of genomic position (NCBI Build 35). The SNP with the strongest signal (rs10830963) is denoted by a blue diamond. Estimated recombination rates (from HapMap) are plotted to reflect the local linkage disequilibrium structure around associated SNPs and proxies (according to a white-to-red scale from r2=0 to r2=1; based on pair-wise r2 values from HapMap CEU). Gene annotations were taken from the University of California-Santa Cruz genome browser.