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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: Mol Biosyst. 2006 Nov 20;3(1):43–50. doi: 10.1039/b611612d

Fig. 2.

Fig. 2

Stability of 100 μM capped siRNA in 10% mouse serum at room temperature. (a) MALDI-TOF mass spectra acquired using matrix a. Capped siRNA and mouse serum controls, capped siRNA incubated with 10% serum at room temperature for 5 min, 15 min, 1 h and 3 h, showing decomposition of the full length strands into shorter fragments (refer to the table). The same laser power was used for all spectra shown (b) 20% PAGE gel of capped siRNA incubated with 10% mouse serum at room temperature at 5–360 min time intervals. Con = untreated capped siRNA control.