TABLE 1.

I₅₀ values for the inhibition of selected protein kinases by BX795

Data are presented as the average of duplicate determinations. VEGFR, vasoendothelial growth factor receptor.

Kinase	IC50	ATP
	μm	μm
TBK1	0.006 ± 0.001	100
IKKε	0.041 ± 0.001	100
PDK1	0.111 ± 0.013	100
Aurora B	0.031 ± 0.002	100
ERK8	0.140 ± 0.027	100
MARK3	0.081 ± 0.008	100
MARK1	0.055 ± 0.004	100
MARK2	0.053 ± 0.005	100
MARK4	0.019 ± 0.001	100
NUAK1	0.005 ± 0.001	100
VEGFR	0.157 ± 0.011	100
MLK1	0.050 ± 0.003	100
MLK2	0.046 ± 0.011	100
MLK3	0.042 ± 0.005	100
TAK1	0.70 ± 0.14	100
ASK1	0.620 ± 0.004	100