FIGURE 2.

Effector binding pocket of SmeT. a, the figure shows the secondary structure of subunit A of SmeT in pale brown, and the binding pocket is represented in magenta. Pathways leading to this cavity were calculated using CAVER and are represented using PYMOL. b, the surface of SmeT subunit A is in green, and subunit B is in blue, showing the entrance between helices 4, 5, and 6. The binding pocket for subunit A is represented in magenta. c, stereo view of the residues lining the hydrophobic cavity of SmeT.