Fig. 2.
Peripheral blood CD4+ T cell profiles and viral nucleic acid levels during the acute SIV and SHIV infections of macaques. (A) Circulating CD4+ T cell numbers and plasma viral RNA loads were measured in a SIV (CN30)-infected and a SHIVDH12R (WGG)-infected rhesus monkey at the indicated times. (B) PBMC samples, collected on days 7 and 10 PI from macaques CN30 and WGG, were stained with anti-CD3, CD4, CD28, and CD95 mAbs to distinguish naïve from memory CD4+ T cells and sorted by FACS for determinations of the cell-associated viral DNA copies per 105 cells by DNA PCR.