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. 2009 Apr 20;106(19):7702–7707. doi: 10.1073/pnas.0901054106

Fig. 3.

Fig. 3.

Discrimination of a single adenine nucleotide by αHL. The graph (Middle) indicates the differences in residual current (ΔIRES values) between blockades caused by a poly(dC) oligonucleotide containing a single adenine nucleotide (the sequence of each oligonucleotide is shown to the left) and blockades caused by poly(dC)40 for WT (green) and E111N/K147N (orange) αHL pores (see also Table S4). R1, R2 and R3 represent the 3 proposed recognition sites in the αHL nanopore. Their probable locations are indicated on the cross-section of the β barrel domain of the αHL pore (Right).