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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: Respir Physiol Neurobiol. 2008 Nov 14;166(1):4–12. doi: 10.1016/j.resp.2008.11.005

FIGURE 6.

FIGURE 6

The effect of carbenoxolone on the percentage of neurons that responded to hypercapnia in neurons from young (P1–P9) (A) and older (P10–P19) (B) neonatal rats. (A) The percentage of NTS neurons that did not change firing rate (white bars), that were activated by (gray bars) and that were inhibited by (black bars) hypercapnia is shown for young (P1–P9) neonatal rats in the absence (CONTROL) and the presence (CARBENOXOLONE) of 100 μM carbenoxolone. Although there was a slight decrease in the number of NTS neurons activated by hypercapnia in the presence of carbenoxolone it was not significant (P=0.08; contingency table with Fisher’s exact test). (B) The percentage of NTS neurons that did not change firing rate (white bars), that were activated by (gray bars) and that were inhibited by (black bars) hypercapnia is shown for older (P10-P19) neonatal rats in the absence (CONTROL) and the presence (CARBENOXOLONE) of 100 μM carbenoxolone. Note that the percentage of neurons that responded to hypercapnia was unaffected by carbenoxolone in these older neonates. In both figures, the total number (N) of neurons in each group is given in the bar.