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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Exp Eye Res. 2009 Jan 7;88(6):1004–1013. doi: 10.1016/j.exer.2008.12.013

Figure 1.

Figure 1

Vascular development and microglia distribution occurs normally in CX3CR1+/− and CX3CR1−/− animals. At postnatal day (P) 0, the hyaloid vasculature is seen prominently and vasculogenesis in the retina extends only to the superficial central retina in both genotypes (A, B). Microglia are concentrated at the optic nerve and the retinal ganglion cell layer (GCL), with scattered microglia migrating into the neuroblastic layer (NBL) (C, D). At P7, vascular development progresses towards the peripheral and outer layers of the retina (E, F). Microglia are found in close association with retinal vessels and in a laminated distribution in the GCL, inner plexiform layer (IPL), inner nuclear layer (INL), and outer plexiform layer (OPL), similarly between both genotypes (G, H).