Fig. 6.
In vascular segments pre-contracted with phenylephrine (PE, 1 μM) cumulatively applied β-NAD (A, B), adenosine (ADO, C, D), and ATP (E, F) induced changes in the smooth muscle tone of canine isolated mesenteric artery (left column) and vein (right column); panels A–F represent original traces from mechanical experiments. Panels G and H show average changes in smooth muscle tone expressed as percentage from the PE contraction. Data represent mean±SEM from 6–14 experiments. The asterisks denote significant difference from control PE contractions, P<0.05.