Table 1. Baseline Variables Reported in Each of Papers Describing the Main Findings and Clinical Subgroup Analyses of V-HeFT I and V-HeFT II.

Baseline Variable	Main Findings		Subgroup Analyses
	V-HeFT I	V-HeFT II	Clinical V-HeFT I	Clinical V-HeFT II	Racial V-HeFT I & II
	Cohn et al. 19868	Cohn et al. 19919	Cohn et al. 198714	Johnson et al. 199315	Carson et al. 19997
Age	+	+	+	+	+
Heart failure symptoms	+	+	-	-	-
Angina in last month	+	-	-	-	-
Coronary artery disease	+	+	+	+	+
Previous myocardial infarction	+	+	-	-	-
Alcohol excess	+	+	+	+	-
Hypertension	+	+	+	+	+
Diabetes	+	+	-	-	-
Coronary bypass surgery	+	+	+	-	-
Valve replacement surgery	+	-	-	-	-
Vasodilator therapy	+	+	+	+	-
Antiarrhythmic therapy	+	+	+	+	-
Sublingual nitroglycerine	+	+	-	-	-
Anticoagulant therapy	+	+	-	+	-
Symptom score1	+	-	-	-	-
Arterial pressure	+	+	-	-	-
Heart rate	+	+	-	+	+2
Cardiothoracic ratio	+	+	+	+	+
Ejection fraction	+	+	+	+	+
Left ventricular internal diastolic diameter	+	+	+	+	-
Exercise duration	+	-	-	-	-
Maximum O2 consumption	+	+	+	+	+
New York Heart Association class	-	+	-	+	-
Race	-	+	-	-	-
Cerebrovascular accident	-	+	-	-	-
Tobacco use	-	+	-	-	-
Atrial fibrillation	-	+	-	-	-
S3 gallop	-	+	-	-	-
Plasma norepinephrine	-	-	-	+	+3
Plasma renin activity	-	-	-	+	+3
Cardiac hospitalization	-	-	-	+	-
Arrhythmia severity	-	-	-	+	-
Weight	-	-	-	+	-
Quality-of-life score	-	-	-	+	-
Systolic blood pressure	-	-	-	+	+
Diastolic blood pressure	-	-	-	+	+

¹Sum of scores for dyspnea, fatigue, orthopnea, and paroxysmal nocturnal dyspnea

²Only included in the racial subgroup analysis of V-HeFT I

³Only included in the racial subgroup analysis of V-HeFT II