U0126 blocks FGF-induced lens cell elongation. Representative micrographs of cells in lens explants not exposed to growth factors (A,B) or exposed to 100 ng/ml of FGF (C,D), in the presence of U0126 (B,D), labelled with TRITC-conjugated lectin. After 5 days culture, FGF-induced cell elongation (C) was effectively blocked in the presence of U0126 (D), with cells retaining an epithelial cobblestone morphology. Scale bar, 50μm.