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. Author manuscript; available in PMC: 2010 Feb 19.
Published in final edited form as: Org Lett. 2009 Feb 19;11(4):899–902. doi: 10.1021/ol802844z

Table 1.

Effect of Equivalents of Amines and Pd(0) Sources.

graphic file with name nihms91595t1.jpg
entry graphic file with name nihms91595t2.jpg Inline graphic [mol %] amine equiv time [h] yield [%]a 7 8
1 Pd(PPh3)2Cl2 -- 5.0 2 92 5
2 -- 3.0 2 63 24
3 -- 1.0 2 44 45
4 -- 1.0: syringe pump addition 2 11 73
5 Pd(PPh3)4 -- 3.0 3 0 ≥95
6 Pd(dppe)Cl2 -- 3.0 48 30 <5
7 Pd(dppf)Cl2 -- 3.0 24 95 0
8 Pd2(dba)3 Inline graphic [10.0] 3.0 24 40 59
9 Pd2(dba)3 Inline graphic [10.0] 3.0 3 0 ≥95
10 Pd2(dba)3 Inline graphic [10.0] 3.0 24 <5 95
graphic file with name nihms91595t3.jpg
a

All are isolated yields.