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Expression of phase I bile acid biosynthesis and metabolizing genes. Hepatic Cyp3a11, Cyp7a1, Cyp7a1, Cyp8a1, Cyp27a1, and Cyp39a1 mRNA levels in each treatment group were quantified by the bDNA signal amplification assay, as described under Materials and Methods. Data are expressed as relative light units (RLU) ± S.E.M. *, indicates p ≤ 0.05 compared with respective CO; †, indicates p ≤ 0.05 compared with respective LCA only.
