Table V.
Serum cytokine profile between fatal and recovered SARSa
| Fatal SARS | Recovered SARS | p | |
|---|---|---|---|
| Patients (n) | 11 | 87 | |
| Th1 cytokines (pg/ml) | |||
| IFN-γ | 22.4 ± 8.0 | 28.2 ± 6.50 | NS |
| IL-2 | 0.92 ± 0.30 | 0.87 ± 0.20 | NS |
| TNF-α | 1.85 ± 0.33 | 1.24 ± 0.53 | NS |
| IL-12 | 6.33 ± 2.29 | 19.4 ± 9.83 | NS |
| Th2 cytokines (pg/ml) | |||
| IL-4 | 6.63 ± 0.84 | 3.42 ± 0.66 | <0.001 |
| IL-5 | 2.81 ± 0.97 | 0.64 ± 0.12 | 0.04 |
| IL-10 | 13.2 ± 5.16 | 9.05 ± 1.97 | 0.05 |
| Inflammatory cytokines (pg/ml) | |||
| IL-1 | 9.01 ± 2.09 | 29.4 ± 8.41 | 0.04 |
| IL-6 | 27.7 ± 11.9 | 47.7 ± 8.99 | NS |
| IL-8 | 159.7 ± 116 | 48.8 ± 7.15 | 0.03 |
a
Recovered and fatal SARS groups were described using the geometric mean ratio and 95% confidence intervals. ANOVA with age as a covariate (ANCOVA) was used for comparisons of variables between groups of patients. Unequal variances were taken into account by the t test for comparison of two samples.