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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Neurobiol Dis. 2008 Aug 5;32(2):309–318. doi: 10.1016/j.nbd.2008.07.014

Figure 6. Dendritic spine number was preserved while spine density was decreased in cells from Tg2576 mice.

Figure 6

A. Images of apical (top) and basal (bottom) dendritic branch and spine reconstructions from representative Wt (left) Tg2576 (right) cells. B. Bar graphs (left) and Sholl analysis (right) demonstrating no significant difference in the total spine numbers in the apical and basal trees in Wt vs. Tg2576 cells. C. Bar graphs (left) and Sholl analysis (right) demonstrating a significant decrease in spine density on both apical and basal dendritic trees in Tg2576 cells. * p < 0.02. D. Scatter plots of spine number (left) and spine density (middle) vs. total cell volume for individual cells, demonstrating a significant relationship with total cell volume for spine number (R = 0.57; p < 0.02) but not density (R = 0.38; p = 0.14). Scale bar in A = 7 µm.