Table 1.
PsC vs. control (3523 cases, 5942 controls) |
PsA vs. control (1755 cases, 5942 controls) |
PsA vs. PsC (1755 cases, 3523 controls) |
|||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Marker | Chr | Position (bld 36.1) |
Nearby Notable Gene |
Alleles (risk/ nonrisk) |
· | freq cases |
freq controls |
meta OR |
meta allelic p-value |
freq cases |
freq controls |
meta OR |
meta allelic p-value |
freq cases |
freq controls |
meta OR |
meta allelic p-value |
rs12191877 | 6 | 3.1E+O7 | HLA-C | T/C | 0.316 | 0.139 | 2.87 | 2.98E-178 | 0.260 | 0.139 | 2.34 | 6.26E-62 | 0.260 | 0.316 | 0.87 | 6.14E-03 | |
rs2082412 | S | I.6E+O8 | 1L12B | G/A | 0.846 | 0.797 | 1.42 | 4.57E-18 | 0.861 | 0.797 | 1.63 | 3.90E-16 | 0.861 | 0.846 | 1.19 | 9.51E-03 | |
rs17728338 | 5 | 1.5E+O8 | TNIP1 | A/G | 0.083 | 0.054 | 1.56 | 1.40E-13 | 0.100 | 0.054 | 1.78 | 2.32E-14 | 0.100 | 0.083 | 1.15 | 7.43E-02 | |
rs20541 | 5 | 1.3E+O8 | IL13 | G/A | 0.821 | 0.787 | 1.24 | 3.77E-08 | 0.833 | 0.787 | 1.34 | 1.35E-07 | 0.833 | 0.821 | 1.10 | 1.13E-01 | |
rs610604 | 6 | 1.4E+08 | TNFAIP3 | G/T | 0.364 | 0.318 | 1.23 | 3.O7E-1O | 0.362 | 0.318 | 1.18 | 2.94E-04 | 0.362 | 0.364 | 0.98 | 6.70E-01 | |
rs2O668O7 | 12 | 5.5E+O7 | IL23A | C/G | 0.949 | 0.932 | 1.33 | 1.9OE-O5 | O.955 | 0.932 | 1.55 | 9.49E-06 | 0.955 | 0.949 | 1.15 | 2.25E-01 | |
rs2201841 | 1 | 6.7E+07 | IL23R | G/A | 0.340 | 0.295 | 1.23 | 1.75E-1O | 0.318 | 0.295 | 1.07 | 1.42E-01 | 0.318 | 0.340 | 0.89 | 1.50E-02 |