Figure 8.

Manganese transport after isotonic MnCl₂ injections into ACC of monkey S. On postinjection day 4, manganese was detected ipsilaterally throughout area 24c, in dlPFC (area 46V), OFC (area 13), and regions on the medial wall (areas 24b and 32). Subcortical signal was found ipsilaterally in dorsal caudate (Cd) and putamen (Pu), globus pallidus externa and interna (GPe/GPi), ventral pallidum (VP), and ventral anterior nucleus of the thalamus (VA; transport seen in the medial dorsal nucleus of the thalamus not pictured). There was also manganese signal within the corpus callosum (cc), and manganese accumulation contralateral to the injection site in the internal capsule (ic), rostral putamen, and globus pallidus externa. On postinjection day 7, manganese signal remained around the injection site in dorsal caudate and putamen and in globus pallidus externa and interna. Image acquisition parameters are as in Figure 4. Statistical mapping conventions are as in Figure 5 (t test, p ≤ 0.01, all corrected for multiple comparisons). Scale bars, 10 mm.