Fig. 2.

Immunoblot (A) and densitometric analysis (B) of highly purified CYP2D6.1 and CYP2D6.2 suggests that CYP2D6 total protein levels are similar in the two samples; 0.1, 0.25, 0.5, 1.0, or 2.0 pmol holoprotein of each isozyme was loaded into each well, and proteins were separated by SDS-PAGE. Immunoblot analyses were carried out using a selective antibody against CYP2D6.