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Illustration of relative quantification of CYP2D6.2 versus CYP2D6.1 by DeCyder MS using a matched tryptic peptide (FGDIVPLGVTHMTSR; in the highlighted areas) existing in both isozymes. Top, zoom view of paired MS1 signals (m/z versus retention time); bottom, the three-dimensional integration of the representative peptide at all the charge states.
