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. 2009 Mar 12;28(8):1142–1156. doi: 10.1038/emboj.2009.60

Figure 8.

Figure 8

Model for role of the MRX complex at stalled forks. The MRX complex is present at stalled replication forks and is important for fork recovery. The MRX complex is important for the association of DNA polymerase α and ɛ and possibly other replisome factors (represented by the hexagon) with stalled forks. In the absence of the MRX complex and of properly established SCC, sister chromatids are not held together, and this has a destabilizing influence on the fork resulting in a loss of fork recovery and cell viability.