. Author manuscript; available in PMC: 2009 Jul 1.

Published in final edited form as: Nat Methods. 2009 Jan;6(1):39–46. doi: 10.1038/nmeth.1284

Table 1.

Comparison of s trategies towards completing an interactome map

Attribute	High-throughput	Literature Curated
Investigation	discovery based	hypothesis driven
Functional inference	determinable from network?	determinable from study design?
Study bias	unbiased	biased
Completeness	estimable	inestimable
Reliability	determinable	indeterminable