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[14C]Sucrose-corrected uptake of [3H]pentamidine in brain regions and capillary depletion samples of FVB-mdr 1a/1b(+/+) compared with FVB-mdr 1a/1b(-/-) mice (A) and CF-1 mdr1a(+/+) compared with CF-1 mdr1a(-/-) mice (B). Perfusion time, 30-min perfusion. Each data point represents n = 5to12. *, P < 0.01; **, P ≤ 0.001 compared with wild-type strains.
