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NFV was significantly depleted by cDNA-expressed CYP3A64 enzyme. The depletion was significantly inhibited by 0.5 mM ERY or 0.5 μM KTZ but not by 3 μM SUL (A). NFV depletion was also significantly inhibited by various concentrations of TAO (0.01–1 mM) (B). Data were compared using paired two-sample Student's t test. *, p < 0.05; **, p < 0.01.
