Fig. 1.

Static model. (A) HE image of a soleus axial cross-section showing the isotropic and homogeneous porous architecture and uniform interstitial spacing under 0% and 20% strains. A myofiber is outlined. (B) Two dimensional depiction of the homogeneous muscle axial cross-section with myofibers idealized by a regularly repeating lattice of staggered diamonds (white) interspaced with interstitial channels (pink) of consistent width. Symmetry of the problem allowed the computation to be carried out on a reduced domain, Ω, formed by a single lattice arrangement of diamonds (inset) with (C) boundaries Γ₁ and Γ₂. (D) HE image of the inhomogeneous fiber arrangement with wide interstitial channels (green) separating fascicles (black) of myofibers that occur under 5%, 10%, and 15% strains. (E) Depiction of the inhomogeneous muscle cross-section with a wide interstitial channel added to the regular lattice. Location of the channel with respect to the diamonds did not significantly influence transport.