Skip to main content
. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Exp Neurol. 2009 Mar 5;217(2):242–251. doi: 10.1016/j.expneurol.2009.02.011

Figure 4. Microglial proliferation and RGM expression in response to spinal cord transection.

Figure 4

A, Increase in the number of fluorescein-labeled GSL I–isolectin B4 microglial cells in the spinal cord between 0.5 and 5 mm rostral and caudal to the lesion site at 14 and 30 days post-lesion. P-values are indicated as follows: * P < 0.05 compare to control. Differences between 14 days and 30 days numbers are not significant. Data are presented as mean with standard deviation and analyzed using a one way ANOVA followed by Tukey’s multiple comparison test. B, Temporal and spatial dependence of RGM expression in microglial cells post-transection. The number of RGM-expressing microglial cells at 2 and 4 weeks post-transection are compared between control and lesioned spinal cord 0.5, 1 and 5 mm from the transection. Control vs. 2 weeks: * P<0.001; control vs. 4 weeks: P>0.05, ns, not significant; 2 weeks vs. 4 weeks: ** P<0.001. Data are presented as means and standard deviations and analyzed using a two way ANOVA followed by a Bonferroni post-test.