Figure 2. Astrocytic ensheathment of cerebrovasculature.
A, two-photon fluorescence image of astrocytes (green) and blood vessels (red) in rat neocortex, stained using the astrocyte-specific marker SR101 and tail-vein injection of FITC-labelled dextran, respectively. Unstained neuronal cell bodies (arrowheads) appear as dark gaps. Scale bar, 20 μm. B, higher magnification fluorescence image showing how astrocytic end feet ensheath almost the entire cerebrovascular surface. Scale bar, 10 μm. Figure modified from Nimmerjahn et al. (2004), with permission from Macmillan Magazines Ltd, © 2004.