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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Int J Oncol. 2009 May;34(5):1319–1327.

Figure 2.

Figure 2

Curcumin (30 μM) blocks the effects of PMA on PC-3 cell adhesion, motility and invasion. Adhesion assays were performed fibronectin (A), collagen (B), or laminin (C) using either 30 min (black bars) or 60 min (white bars) incubations. The motility (D) and invasion (E) assays were performed using a transwell system incubated for 18 hr in the absence and presence of matrigel, respectively. The results are presented as the percentage of vehicle-treated control. Each bar represents the mean ± SEM of 2-3 independent experiments. See Materials and methods for statistical analysis. *, p< 0.05 compared to vehicle-treated control cells. †, p< 0.05 compared to PMA-treated cells. Abbreviations: cur: curcumin, PMA: phorbol 12-myristate 13-acetate.