Actions of eicosanoids: from the enzymes to the main effects through the superfamily of metabolic products (simplified pathway) Copyright © 2002. Modified with permission from Bertolini A, Ottani A, Sandrini M. 2002. Selective COX-2 inhibitors and dual acting anti-inflammatory drugs: critical remarks. Curr Med Chem, 9:1033–43.
Abbreviations: COX, cyclooxygenase; LOX, lipoxygenase.