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The immune system in the elderly. The function and parameters which change during aging are summarized in this figure.
Abbreviations: CMV, cytomegalovirus; DISC, death-inducing signaling complex; IL-2, interleukin-2; KLRG-1, killer cell lectin-like receptor subfamily G member 1; NF-AT, nuclear factor of activated T cells; NF-κB, nuclear factor κB; MAPK, mitogen-activated protein kinase; PKC, protein kinase C, TCR, T cell receptor.
