Table 1.

Patient characteristics

Group	N (boys/girls)	Age years (a)	Height SDS	Target height SDS (b)	Growth rate SDS (c)	BMI SDS	GH peak ng/ml (a)	IGF-1 zs
1. GHD with PSIS	53 (31/22)	4.7 ± 4.0 [0.02;17]	-2.5 ± 1.4 [-6.2; 0.8]	-0.2 ± 0.8 [-1.7;1.5]	-2.2 ± 1.4 [-4.3;1.6]	0.19 ± 1.7 [-2.4;6.7]	2.6 ± 1.8 0.0;6.6	-3.8 ± 0.9 -5.5;-2.3
2. Transient GHD	19 (9/10)	9.2 ± 3.0 [1.1;14.0]	-2.8 ± 0.8 [-4.4;-1.5]	-0.8 ± 0.9 [-2.6;0.9]	-1.2 ± 1.0 [-3.5;0.1]	0.32 ± 1.4 [-1.9;3.5]	4.9 ± 1.2 3.0;6.7	-3.2 ± 0.9 -4.8;-1.8

means ± SD [ranges]

Group 1 compared to Group 2: (a) P < 0.0001; (b) P < 0.02; (c) < 0.003

Among the 29 Group 1 patients with other hypothalamic-pituitary deficiencies, 4 had only a TSH deficiency, 10 had TSH and adrenocorticotropin hormone deficiencies, 2 had TSH and gonadotropin deficiencies, and 13 had a complete anterior pituitary deficiency.