Table 4.
Diagnostic accuracy of the pediatric non-alcoholic fatty liver disease fibrosis index.
| Cut-point | n | % | TPR | TNR | PLR | NLR | PPV | NPV |
| ≥ 1 | 198 | 97.5 | 99.3 (96.1 to 100.0) |
6.4 (1.8 to 15.7) |
1.1 (1.0 to 1.1) |
0.1 (0.01 to 1.0) |
70.7 (63.8 to 76.9) |
80.0 (28.4 to 99.5) |
| ≥ 2 | 190 | 93.6 | 97.2 (92.9 to 99.2) |
14.5 (6.9 to 25.8) |
1.1 (1.0 to 1.3) |
0.2 (0.1 to 0.6) |
72.1 (65.2 to 78.4) |
69.2 (38.6 to 90.9) |
| ≥ 3 | 179 | 88.2 | 95.7 (91.0 to 98.4) |
29.0 (18.2 to 41.9) |
1.3 (1.1 to 1.6) |
0.2 (0.1 to 0.3) |
75.4 (68.4 to 81.5) |
75.0 (53.3 to 90.2) |
| ≥ 4 | 167 | 82.3 | 93.6 (88.2 to 97.0) |
43.5 (31.0 to 56.7) |
1.7 (1.3 to 2.1) |
0.2 (0.1 to 0.3) |
79.0 (72.1 to 84.9) |
75.0 (57.8 to 87.9) |
| ≥ 5 | 154 | 75.9 | 88.7 (82.2 to 93.4) |
53.2 (40.1 to 66.0) |
1.9 (1.4 to 2.5) |
0.2 (0.1 to 0.4) |
81.2 (74.1 to 87.0) |
67.3 (52.5 to 80.1) |
| ≥ 6 | 138 | 68.0 | 81.6 (74.2 to 87.6) |
62.9 (49.7 to 74.8) |
2.2 (1.6 to 3.1) |
0.3 (0.2 to 0.4) |
83.3 (76.0 to 89.1) |
60.0 (47.1 to 72.0) |
| ≥ 7 | 118 | 58.1 | 76.6 (68.7 to 83.3) |
83.9 (72.3 to 92.0) |
4.7 (2.7 to 8.4) |
0.3 (0.2 to 0.4) |
91.5 (85.0 to 95.9) |
61.2 (50.0 to 71.6) |
| ≥ 8 | 94 | 46.3 | 62.4 (53.9 to 70.4) |
90.3 (80.1 to 96.4) |
6.4 (3.0 to 13.9) |
0.4 (0.3 to 0.5) |
93.6 (86.6 to 97.6) |
51.4 (41.6 to 61.1) |
| ≥ 9 | 66 | 32.5 | 46.1 (37.7 to 54.7) |
98.4 (91.3 to 100.0) |
28.6 (4.0 to 201.0) |
0.6 (0.5 to 0.6) |
98.5 (91.8 to 100.0) |
44.5 (36.0 to 53.3) |
95% confidence intervals are given in parentheses. Abbreviations: TPR = true positive rate; TNR = true negative rate; PLR = positive likelihood ratio; NLR = negative likelihood ratio; PPV = positive predictive value; NPV = negative predictive value.