Table 1.
Genotype and allele frequencies for 20 SNPs.
| #rs | rs819136 | rs1129414 | rs2075508 | rs10960756 | rs3793976 | ||||||||||
| Allele Type | A/G | A/C | C/T | A/G | G/T | ||||||||||
| Melanin Value | all | high | low | all | high | low | all | high | low | all | high | low | all | high | low |
| Genotypes 1/1 | 0.01 | 0.03 | 0.00 | 1.00 | 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.88 | 0.82 | 0.93 |
| Genotypes 1/2 | 0.18 | 0.11 | 0.20 | 0.00 | 0.00 | 0.00 | 0.18 | 0.13 | 0.20 | 0.01 | 0.00 | 0.02 | 0.12 | 0.18 | 0.07 |
| Genotypes 2/2 | 0.81 | 0.87 | 0.80 | 0.00 | 0.00 | 0.00 | 0.82 | 0.87 | 0.80 | 0.99 | 1.00 | 0.98 | 0.00 | 0.00 | 0.00 |
| Alleles 1 | 0.10 | 0.08 | 0.10 | 1.00 | 1.00 | 1.00 | 0.09 | 0.07 | 0.10 | 0.00 | 0.00 | 0.01 | 0.94 | 0.91 | 0.97 |
| Alleles 2 | 0.90 | 0.92 | 0.90 | 0.00 | 0.00 | 0.00 | 0.91 | 0.93 | 0.90 | 1.00 | 1.00 | 0.99 | 0.06 | 0.09 | 0.03 |
| #rs | rs2298458 | rs3212363 | rs1805008 | rs3212371 | rs2279727 | ||||||||||
| Allele Type | G/T | A/T | C/T | A/G | A/C | ||||||||||
| Melanin Value | all | high | low | all | high | low | all | high | low | all | high | low | all | high | low |
| Genotypes 1/1 | 0.94 | 0.97 | 0.90 | 0.52 | 0.47 | 0.54 | 0.89 | 0.87 | 0.92 | 0.80 | 0.74 | 0.83 | 0.92 | 0.89 | 0.95 |
| Genotypes 1/2 | 0.06 | 0.03 | 0.10 | 0.44 | 0.50 | 0.42 | 0.11 | 0.13 | 0.08 | 0.20 | 0.26 | 0.17 | 0.08 | 0.11 | 0.05 |
| Genotypes 2/2 | 0.00 | 0.00 | 0.00 | 0.03 | 0.03 | 0.03 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Alleles 1 | 0.97 | 0.99 | 0.95 | 0.75 | 0.72 | 0.75 | 0.94 | 0.93 | 0.96 | 0.90 | 0.87 | 0.92 | 0.96 | 0.95 | 0.97 |
| Alleles 2 | 0.03 | 0.01 | 0.05 | 0.25 | 0.28 | 0.25 | 0.06 | 0.07 | 0.04 | 0.10 | 0.13 | 0.08 | 0.04 | 0.05 | 0.03 |
| #rs | rs4778182 | rs1800419 | rs2311843 | rs1800414 | rs1800404 | ||||||||||
| Allele Type | A/G | C/T | C/T | A/G | A/G | ||||||||||
| Melanin Value | all | high | low | all | high | low | all | high | low | all | high | low | all | high | low |
| Genotypes 1/1 | 0.16 | 0.24 | 0.14 | 0.14 | 0.16 | 0.14 | 0.73 | 0.82 | 0.71 | 1.00 | 1.00 | 1.00 | 0.61 | 0.71 | 0.58 |
| Genotypes 1/2 | 0.53 | 0.53 | 0.58 | 0.49 | 0.39 | 0.54 | 0.26 | 0.18 | 0.25 | 0.00 | 0.00 | 0.00 | 0.31 | 0.21 | 0.34 |
| Genotypes 2/2 | 0.31 | 0.24 | 0.29 | 0.37 | 0.45 | 0.32 | 0.02 | 0.00 | 0.03 | 0.00 | 0.00 | 0.00 | 0.07 | 0.08 | 0.08 |
| Alleles 1 | 0.42 | 0.50 | 0.42 | 0.39 | 0.36 | 0.41 | 0.85 | 0.91 | 0.84 | 1.00 | 1.00 | 1.00 | 0.77 | 0.82 | 0.75 |
| Alleles 2 | 0.58 | 0.50 | 0.58 | 0.61 | 0.64 | 0.59 | 0.15 | 0.09 | 0.16 | 0.00 | 0.00 | 0.00 | 0.23 | 0.18 | 0.25 |
| #rs | rs7623610 | rs704246 | rs16964944 | rs1724577 | rs4776053 | ||||||||||
| Allele Type | A/G | C/T | A/G | G/T | C/T | ||||||||||
| Melanin Value | all | high | low | all | high | low | all | high | low | all | high | low | all | high | low |
| Genotypes 1/1 | 0.30 | 0.35 | 0.26 | 0.61 | 0.58 | 0.63 | 1.00 | 1.00 | 1.00 | 0.99 | 0.97 | 1.00 | 0.69 | 0.58 | 0.75 |
| Genotypes 1/2 | 0.39 | 0.24 | 0.43 | 0.32 | 0.29 | 0.32 | 0.00 | 0.00 | 0.00 | 0.01 | 0.03 | 0.00 | 0.29 | 0.39 | 0.24 |
| Genotypes 2/2 | 0.31 | 0.41 | 0.31 | 0.07 | 0.13 | 0.05 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.02 | 0.03 | 0.02 |
| Alleles 1 | 0.50 | 0.47 | 0.47 | 0.77 | 0.72 | 0.79 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 0.83 | 0.78 | 0.86 |
| Alleles 2 | 0.50 | 0.53 | 0.53 | 0.23 | 0.28 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.17 | 0.22 | 0.14 |
Note: 1) In case of allele type ○/□, 1/1→○/○, 1/2→○/□, 2/2→□/□.
2) Melanin Value: all→all subjects, high→the group with high value of melanin, low→the group with low value of melanin