Figure 3.

Mosaic relationships of the rhodopsin GPCR groups. Instances of phylogenetic mosaicism between GPCR groups are displayed. Colour signifies the major group from which the mosaic fragment derives: blue, nucleotide receptor group (A); pink, endocrine receptor group (B); orange, opioid receptor group (C); purple, neuropeptide receptor group (D); red, mas receptor group (E); green amine receptor group (F). Letters A–F correspond to major groups in Fig 2. GPCR groups not associated with a major group are colour coded as follows: group 1, white; group 2b pale blue; group 6c, violet; group 10 brown. Transmembrane domains are indicated in grey over the alignments. For details of specific receptor affiliations see Supplementary Figure 1.