Figure 4.

Mosaicism in opioid receptor group (group 4). Segmental phylogenetic affiliations resulting from HTP. Segments that have phylogenetic affiliations to receptors in GPCR groups other than group 4 are shown as colour blocks with the affiliated receptor name. Block colour corresponds to major GPCR group, shown in Figure 3. Transmembrane domains are indicated in grey over the alignment. For further details of affiliated fragment lengths see Supplementary Figure 1.