Table 1.

Correlations between Clinicopathologic Factors and Specific Protein Markers with Caveolin-1 Expression in the Stromal Compartment of 173 Breast Cancers

	All patients n = 173 (%)	Caveolin-1 positive stroma n = 103 (60%)	Caveolin-1 negative stroma n = 70 (40%)	P value
Median age (27–81 years), n = 162	54	51	57	0.08
Median tumor size (5–90 mm), n = 164	25	25	25	0.7
Tumor stage, n = 165				0.03
T1 (0–20 mm)	64 (39)	41 (42)	23 (34)
T2 (20–50 mm)	94 (57)	54 (56)	40 (59)
T3 (>50 mm)/T4	7 (4)	2 (2)	5 (7)
Lymph node status, n = 169				0.1
N0 (0 nodes)	92 (54)	58 (57)	34 (50)
N1 (1–3 nodes)	47 (28)	30 (30)	17 (25)
N2 (4–9 nodes)	20 (12)	10 (10)	10 (15)
N3 (>9 nodes)	10 (6)	3 (3)	7 (10)
AJCC stage				0.07
I	45 (27)	29 (29)	17 (25)
IIa	62 (38)	40 (39)	34 (23)
IIb	28 (17)	18 (19)	10 (15)
IIIa	22 (13)	11 (11)	11 (16)
IIIc	8 (5)	1 (1)	7 (10)
Age, n = 157				0.1
<50 years	63 (40)	43 (51)	20 (32)
>50 years	94 (60)	51 (54)	43 (68)
ER status, n = 167				0.1
Positive	119 (71)	73 (74)	46 (68)
Negative	48 (29)	26 (26)	22 (32)
PR status, n = 168				0.1
Positive	107 (64)	66 (66)	41 (60)
Negative	61 (36)	34 (34)	27 (40)
Grade, n = 167				0.001
1, well differentiated	48 (29)	37 (38)	11 (16)
2, moderately differentiated	78 (47)	44 (45)	34 (49)
3, poorly differentiated	41 (25)	17 (17)	25 (36)
CerbB2 status n = 160				0.1
Negative	123 (77)	77 (79)	46 (73)
positive	37 (23)	20 (21)	17 (27)
PCNA status, n = 159				0.07
0–40% staining	73 (46)	47 (50)	26 (41)
>40% staining	86 (54)	48 (51)	38 (60)
P53 status, n = 132				0.1
Negative	95 (72)	61 (77)	34 (64)
Positive	37 (28)	18 (23)	19 (36)
P170 status, n = 150				0.2
Negative	19 (13)	11 (12)	8 (13)
Positive	131 (87)	78 (88)	53 (87)
Caveolin-1 tumor expression				0.3
Negative	153 (88)	89 (86)	64 (91)
Positive	20 (12)	14 (14)	6 (9)
Tumor type, n = 162				N/A
Invasive ductal	123 (75)	69 (72)	54 (79)
Lobular	25 (15)	13 (14)	12 (18)
Special types	14 (8)	13 (14)	1 (1)