Figure 8.
ADAM17 is expressed in podocytes and increased glomerular ADAM17 expression is detectable in patients with MN. A: Podocytes were fixed with methanol and immunofluorescence analysis were performed using a monoclonal antibody against ADAM17 and Cy3 coupled secondary antibody (red). B: ADAM17 expression in human normal kidney was visualized by monoclonal antibody against ADAM17 and Cy3 coupled secondary antibody. C: The expression of ADAM17 was visualized in biopsies of patients with MN by monoclonal ADAM17 followed by Cy3 coupled secondary antibody.