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IL-1 signaling affects the quality of repair in excisional wounds. Cutaneous excisional wounds were created in IL-1R KO and wild-type animals. Wounds were harvested at 14 days, after complete closure. A: Photomicrographs of cross sections through the scar. B: Photomicrographs of the epidermal/dermal junction at the healed excisional wound site. C: Histomorphometric analysis of healed excisional wounds. n = 6 animals per group. Mann Whitney’s U-test (P < 0.05).
