Figure 5.

Strain differences in tongue and esophageal lesions after chronic treatment with anti-TGF-β. Tongue and esophageal sections from BALB/c, C57BL/6, SV129, and DBA/2 mice that were treated three times a week for 12 weeks with 10 mg/kg of anti-TGF-β were scored by a veterinary pathologist according to the criteria outlined in Table 2. Graphs represent scores of individual mice in each treatment group for tongue hyperplasia (A), tongue inflammation (B), esophageal hyperplasia (C), and esophageal inflammation (D). Means of the data are also indicated.