Table 1.

Effect of Nasal Administration of Immunodominant Peptide pCol(24-38) on the in Vitro Splenocyte Proliferative Responses from Groups of Experimental Rats Cultured with α3(IV)NC1

Experimental groups	Stimulation index
Positive control (n = 5)	2.7 ± 0.4
Negative control (n = 5)	0.85 ± 0.3
pCol(24-38) (3000 μg) (n = 6)	0.76 ± 0.2*

Results shown represent the mean ± SD of each group at day 28 after immunization. 

^*P < 0.004, positive control versus pCol(24-38) 3000 μg nasally.