Figure 3.
Pericyte association with capillaries and capillary diameters. A–H: Confocal microscopic images of tracheal whole mounts stained for CD31 (green) and desmin (red, pericytes) immunoreactivity isolated from 4-week-old wild-type (A) and EphA2-deficient (B) mice, 6-week-old wild-type (C) and EphA2-deficient (D) mice, 8-week-old wild-type (E) and EphA2-deficient (F) mice, 25-week-old wild-type (G) and EphA2-deficient (H) mice. Arrows indicate capillaries without pericyte coverage. I–K: Pericyte coverage on capillaries (I), the numbers of pericyte bodies per mm capillary length (J), and capillary diameter (K) in 2- to 25-week-old wild-type and EphA2-deficient mice. Values are presented as means ± SEM; n = 5–8 mice per group; *P < 0.05 versus wild-type. Scale bar = 50 μm.
