Figure 5.

Infiltrating leukocytes and inflammatory cytokine mRNA levels in infected airways. Pathogen-free or 14-day M. pulmonis-infected wild-type and EphA2-deficient mice were sacrificed. A–C: The numbers of total cells (A), lymphocytes (B), and neutrophils (C) that infiltrated into bronchoalveolar lavage were counted. D–H: mRNA expression levels of inflammatory cytokines, tumor necrosis factor (D), IL-1α (E), IL-1β (F), IL-6 (G), and KC (H) in trachea were measured by quantitative RT-PCR. Values are presented as means ± SEM; n = 5–8 mice per group; *P < 0.05 versus wild-type. −/−, EphA2-deficient mice.