Table 3.
Diagnostic accuracy of telomerase-based assays
| Number of cases | Type of marker | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|
| Case-control studies | ||||
| Halling et al.[18] | 265 | TA* | 46 | 91 |
| Sanchini et al.[37] | 218 | TA* | 90 | 88 |
| Bravaccini et al.[47] | 212 | TA* | 87 | 66 |
| Sanchini et al.[36] | 200 | TA* | 92 | 81 |
| Saad et al.[23] | 120 | TA* | 84 | 93 |
| Fedriga et al.[35] | 106 | TA* | 89 | 68 |
| Adb El Gawad et al.[21] | 86 | TA* | 80 | 95 |
| Eissa et al.[55] | 200 | TA* | 75 | 92 |
| hTERT | 96 | 96 | ||
| HTR | 92 | 89 | ||
| Weikert et al.[38] | 400 | hTR | 77 | 72 |
| hTERT | 55 | 85 | ||
| Symptomatic patients | ||||
| Kavaler et al.[45] | 151 | TA* | 85 | 66 |
| Landman et al.[25] | 77 | TA* | 80 | 80 |
*
TA performed by TRAP assay