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The human interactome. A polar map showing the largest connected component of the human interactome based on the Rual et al. (2005) yeast two-hybrid high-throughput protein–protein interaction dataset (1307 proteins and 2441 interactions). The modules are numbered from 1 to 32. Some of them were manually annotated (using Polar Mapper), reflecting the biological function of the proteins that constitute them. The modules marked with an asterisk contain annotated submodules.
