Figure 4.

Membrane-interacting proteins module within the human interactome. The local polar map of module 3 in figure 3. Its central theme appears to be membrane-interacting proteins. Note how the submodules (encircled by grey lines) denser in these proteins are found closer together in the circular ordering of the map. See the main text for a biological analysis of this module. To compose this figure, the polar map was exported into an SVG file using Polar Mapper and the graphical highlight around the submodules and relatedness of each protein concerning the module's theme were edited using an external image processing software (Inkscape).