Table 3.

Genotype and allele^a frequencies in 18 populations from lowlands and highlands of Nepal

Population	n	Genotype
		TNF (rs1800629)					FCGRIIA (rs1801274)
		G	GG	GA	AA	pb	C	CC	CT	TT	pb
Baram	38	1.00	1.00			N.Ac	0.37	0.14	0.46	0.40	0.07
Chantyal	23	0.89	0.79	0.21		1.00	0.50	0.25	0.5	0.25	0.08
Chepangd	27	1.00	1.00			N.A	0.20	0.04	0.32	0.62	1.00
Danuwar	30	0.70	0.49	0.42	0.09	0.69	0.05		0.10	0.90	1.00
Dhimal	22	0.89	0.79	0.21		1.00	0.27	0.08	0.20	0.72	0.63
Dura	35	0.96	0.92	0.08		1.00	0.31	0.10	0.43	0.47	1.00
Ghale	25	0.98	0.96	0.04		1.00	0.16		0.13	0.70	1.00
Gurung	46	0.93	0.86	0.14		1.00	0.41	0.17	0.48	0.35	0.23
High Caste Newar	29	1.00	1.00			N.A	0.52	0.27	0.50	0.23	1.00
Kumal	25	0.88	0.77	0.21	0.02	0.29	0.18	0.03	0.30	0.67	1.00
Magar	45	0.94	0.88	0.11	0.01	0.11	0.21	0.05	0.33	0.62	0.38
Majhi Bote	27	0.85	0.72	0.26	0.02	0.45	0.19	0.04	0.31	0.65	0.19
Newar	50	0.99	0.98	0.02		1.00	0.33	0.11	0.44	0.45	0.75
Sherpa	24	0.75	0.56	0.38	0.06	0.59	0.23	0.05	0.35	0.60	0.56
Tamang	48	0.97	0.94	0.06		1.00	0.26	0.07	0.38	0.55	1.00
Thakali	29	0.93	0.86	0.13	0.01	0.10	0.31	0.09	0.43	0.48	1.00
Tharu	34	0.85	0.72	0.25	0.03	0.12	0.25	0.06	0.38	0.56	0.39
Wambule	29	1.00	1.00			N.A	0.16	0.03	0.26	0.71	0.11

^aFrequency of the protective alleles G and C at TNF and FCGRIIA, respectively

^bp values after testing for departure from Hardy-Weinberg equilibrium (random association of alleles in diploid individuals)

^cN.A. not applicable

^dThe populations in bold live in the malarial lowlands of Nepal. The remaining groups live in regions of high altitudes, which are malaria-free