Table 1.
Clinical characteristics of the study subjects
| Normal range | 7 Discordant pairs
|
4 Concordant GD pairs | 7 Concordant healthy pairs | ||
|---|---|---|---|---|---|
| GD | Non-GD | ||||
| No. of individuals | 7 | 7 | 8 | 14 | |
| Age (yr) | 48.9 ± 6.2 | 48.9 ± 6.2 | 45.0 ± 7.1 | 49.3 ± 3.6 | |
| Males, n (%) | 0 (0) | 0 (0) | 4 (50) | 0 (0) | |
| Ever smoker, n (%) | 7 (100) | 7 (100) | 6 (75) | 10 (71) | |
| GD duration (yr) | 17.7 ± 4.5 | 18.7 ± 9.6 | |||
| TSH (mIU/liter) | 0.3–4.0 | 2.8 ± 2.8 | 4.4 ± 4.5 | 2.7 ± 1.3 | 1.8 ± 1.5 |
| T4 (nmol/liter) | 70–140 | 139 ± 16 | 122 ± 28 | 124 ± 14 | 125 ± 20 |
| Free T4 (pmol/liter) | 9.9–17.7 | 14.6 ± 4.0 | 11.2 ± 0.8 | 14.1 ± 2.3 | 12.8 ± 1.5 |
| T3 (nmol/liter) | 1.45–2.5 | 2.0 ± 0.3 | 2.2 ± 0.3 | 1.9 ± 0.2 | 2.1 ± 0.3 |
| Free T3 (pmol/liter) | 4.3–7.4 | 6.0 ± 1.9 | 5.6 ± 0.7 | 6.0 ± 1.5 | 5.5 ± 0.8 |
| Anti-TPO Ab >10 (%) | 2–10 κIU/liter | 3 (43) | 4 (57) | 5 (63) | 2 (14) |
| Anti-TR Ab >0.7 (%) | <0.7 IU/liter | 2 (29) | 0 (0) | 2 (25) | 0 (0) |
Data are expressed as mean ± sd, unless described otherwise. Ab, Antibody.