Table 4.
Percentage IGF-IR+ lymphocytes by subset
Twin pairs discordant for GD
| |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD3+ T cells
|
CD4+ T cells
|
CD8+ T cells
|
CD4+CD45RA+ T cells
|
CD4+CD45RO+ T cells
|
CD8+CD45RA+ T cells
|
CD8+CD45RO+ T cells
|
CD19+ B cells
|
||||||||
Healthy | GD | Healthy | GD | Healthy | GD | Healthy | GD | Healthy | GD | Healthy | GD | Healthy | GD | Healthy | GD |
21 | 30 | 29 | 43 | 5 | 11 | 61 | 80 | 13 | 15 | 14 | 24 | 2 | 4 | 13 | 11 |
34 | 36 | 24 | 39 | 9 | 11 | 40 | 63 | 6 | 11 | 20 | 26 | 1 | 1 | 10 | 11 |
20 | 15 | 24 | 23 | 9 | 6 | 68 | 68 | 16 | 21 | 23 | 12 | 6 | 3 | 12 | 40 |
13 | 29 | 16 | 33 | 6 | 22 | 60 | 74 | 9 | 19 | 17 | 51 | 1 | 9 | 4 | 12 |
23 | 30 | 31 | 33 | 20 | 25 | 45 | 58 | 12 | 6 | 40 | 33 | 5 | 3 | 17 | 15 |
19 | 35 | 23 | 42 | 8 | 20 | 46 | 82 | 5 | 12 | 22 | 24 | 6 | 3 | 5 | 10 |
12 | 49 | 13 | 48 | 5 | 20 | 31 | 77 | 4 | 24 | 7 | 23 | 1 | 9 | 2 | 29 |
Twin pairs concordant for GD
| |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD3+ T cells | CD4+ T cells | CD8+ T cells | CD4+CD45RA+ T cells | CD4+CD45RO+ T cells | CD8+CD45RA+ T cells | CD8+CD45RO+ T cells | CD19+ B cells | ||||||||
32 | 33 | 31 | 37 | 11 | 21 | 60 | 68 | 11 | 13 | 27 | 37 | 6 | 2 | 14 | 16 |
29a | 32 | 27a | 32 | 14a | 45 | 62a | 74 | 15a | 9 | 65a | 56 | 3a | 2 | 32a | 30 |
26a | 26 | 27a | 32 | 15a | 17 | 60a | 80 | 10a | 12 | 15a | 14 | 2a | 2 | 12a | 11 |
19 | 32a | 11 | 54a | 5 | 23a | 58 | 77a | 8 | 14a | 47 | 47a | 2 | 3a | 6 | 17a |
Control twin pairs | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD3+ T cells | CD4+ T cells | CD8+ T cells | CD4+CD45RA+ T cells | CD4+CD45RO+ T cells | CD8+CD45RA+ T cells | CD8+CD45RO+ T cells | CD19+ B cells | ||||||||
21 | 30 | 20 | 22 | 17 | 14 | 54 | 33 | 9 | 15 | 35 | 30 | 1.3 | 12 | 10 | 12 |
18 | 13 | 16 | 10 | 11 | 12 | 50 | 57 | 6 | 9 | 34 | 32 | 7 | 6 | 12 | 5 |
25 | 18 | 25 | 12 | 12 | 9 | 75 | 60 | 6 | 9 | 26 | 26 | 1 | 1 | 9 | 11 |
15 | 10 | 15 | 14 | 3 | 10 | 49 | 35 | 13 | 12 | 28 | 13 | 1 | 1 | 12 | 13 |
25 | 23 | 26 | 23 | 16 | 14 | − | − | − | − | − | − | − | − | − | − |
15 | 19 | 13 | 20 | 11 | 9 | 21 | 60 | 5 | 13 | 12 | 26 | 3 | 5 | 8 | 9 |
17 | 28 | 20 | 22 | 7 | 20 | 71 | 68 | 9 | 8 | 21 | 56 | 1 | 9 | 14 | 6 |
Peripheral blood mononuclear cells were analyzed by flow cytometry as described. Data from each subject are presented. −, Not determined.
TAO.