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Effect of API-59 on cell proliferation and viability. A, Leiomyoma cells were treated with 100 nm or 1 μm of API-59 with or without 100 nm R5020 for 24 h. Cell proliferation was measured using BrdU incorporation assay. B, A Leiomyoma cells were treated with 3 or 6 μm of API-59. The number of viable cells was measured using the cell viability assay. Data are the mean ± sem of four experiments.
