Figure 1.

Effect of glucose-sweetened beverages (solid lines) and fructose-sweetened beverages (dashed lines) on plasma concentrations of fructose (A), glucose (B), lactate (C), and free fatty acid levels (D) in obese men and women consuming beverages with meals (mean ± sem, n = 17). Fructose was undetectable on the day glucose-sweetened beverages were consumed. Plasma glucose levels were significantly lower (F = 9.0, P < 0.00001, time × treatment), and plasma lactate levels were elevated (F = 13.7 P < 0.00001, time × treatment) after fructose compared with glucose consumption. No significant differences were observed in plasma free fatty acid concentrations between treatments.