Figure 2.

Effect of glucose-sweetened beverages (solid lines) andfructose-sweetened beverages (dashed lines) on plasma concentrations of insulin (left panel) and the percent change of plasma leptin from baseline (right panel) in obese human subjects (mean ± sem, n = 17). Plasma insulin (F = 2.15, P < 0.003, time × treatment) and leptin levels (F = 2.55, P < 0.00001, time × treatment) were significantly lower after fructose compared with glucose consumption. Baseline leptin values were 20.7 ± 10.69 (HGl) and 20.3 ± 11.0 (HFr).